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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCNKB
All Species:
23.94
Human Site:
S542
Identified Species:
47.88
UniProt:
P51801
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51801
NP_000076.2
687
75446
S542
I
L
G
R
N
I
G
S
H
R
V
R
V
E
H
Chimpanzee
Pan troglodytes
XP_525229
687
75266
S542
I
L
G
R
N
I
G
S
H
H
V
R
V
E
H
Rhesus Macaque
Macaca mulatta
XP_001091784
740
81203
S542
I
L
G
R
N
I
S
S
H
R
V
R
V
E
H
Dog
Lupus familis
XP_544547
687
75469
S542
I
R
G
R
K
I
S
S
H
R
V
I
V
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUB6
687
75039
S542
I
R
G
R
Q
I
G
S
H
S
V
T
V
G
H
Rat
Rattus norvegicus
Q06393
687
75551
S542
I
R
G
R
Q
I
G
S
Y
P
V
T
V
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425749
696
76448
S540
I
R
S
R
H
I
A
S
Y
R
V
V
V
K
E
Frog
Xenopus laevis
NP_001079308
689
76782
S544
I
R
S
R
D
I
D
S
Y
K
V
N
T
E
E
Zebra Danio
Brachydanio rerio
NP_956676
693
75983
L558
L
I
R
A
C
P
K
L
A
D
V
Q
I
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
M654
L
L
P
S
S
S
G
M
Y
S
I
F
V
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P60300
763
83497
N583
T
G
P
L
Q
V
F
N
G
I
E
K
V
E
T
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
K627
V
H
G
F
P
I
T
K
D
E
D
K
F
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
85.2
86.1
N.A.
80.4
81.3
N.A.
N.A.
60
61.5
43.5
N.A.
27.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.4
88.6
92.4
N.A.
89
89.9
N.A.
N.A.
73.8
78.2
61.9
N.A.
39.9
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
66.6
66.6
N.A.
N.A.
46.6
40
6.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
66.6
73.3
N.A.
N.A.
66.6
60
40
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
0
9
9
9
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
9
0
0
75
17
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
9
9
0
0
% F
% Gly:
0
9
59
0
0
0
42
0
9
0
0
0
0
9
0
% G
% His:
0
9
0
0
9
0
0
0
42
9
0
0
0
0
50
% H
% Ile:
67
9
0
0
0
75
0
0
0
9
9
9
9
0
0
% I
% Lys:
0
0
0
0
9
0
9
9
0
9
0
17
0
17
9
% K
% Leu:
17
34
0
9
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
17
0
9
9
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
25
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
0
42
9
67
0
0
0
0
0
34
0
25
0
0
0
% R
% Ser:
0
0
17
9
9
9
17
67
0
17
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
9
0
0
0
0
17
9
0
9
% T
% Val:
9
0
0
0
0
9
0
0
0
0
75
9
75
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _